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                             200 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Acknowledgements
32 S7 p. viii
artikel
2 Editorial Board
32 S7 p. i
artikel
3 ESMO
32 S7 p. v-vi
artikel
4 Journal Information
32 S7 p. ii
artikel
5 LBA1 BNT211: A phase I/II trial to evaluate safety and efficacy of CLDN6 CAR-T cells and CARVac-mediated in vivo expansion in patients with CLDN6+ advanced solid tumors Haanen, J.

32 S7 p. S1392
artikel
6 LBA3 Safety and efficacy of pembrolizumab combined with paclitaxel and cisplatin as a neoadjuvant treatment for locally advanced resectable (stage III) esophageal squamous cell carcinoma (Keystone-001): Interim analysis of a prospective, single-arm, single-center, phase II trial Shang, X.

32 S7 p. S1428-S1429
artikel
7 LBA4 The efficacy and safety of TQ-B2450 alone/with anlotinib in previously treated advanced non-small cell lung cancer (NSCLC): A multicenter, randomized, double-blind, placebo-controlled clinical trial Han, B.

32 S7 p. S1429
artikel
8 LBA2 Updated analysis and patient-reported outcomes (PROs) from CITYSCAPE: A randomised, double-blind, phase II study of the anti-TIGIT antibody tiragolumab + atezolizumab (TA) versus placebo + atezolizumab (PA) as first-line treatment for PD-L1+ NSCLC Cho, B.C.

32 S7 p. S1428
artikel
9 47MO Metabolic intervention during CAR T-cell manufacturing improves persistence and antitumor efficacy Wenes, M.

32 S7 p. S1393
artikel
10 123MO Monalizumab, cetuximab and durvalumab in first-line treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN): A phase II trial Colevas, D.A.

32 S7 p. S1432
artikel
11 122MO Nivolumab (NIVO) + ipilimumab (IPI) as first-line (1L) treatment (tx) for patients (pts) with advanced NSCLC (aNSCLC) and baseline (BL) brain metastases (mets): Intracranial and systemic outcomes from CheckMate 227 Part 1 Reck, M.

32 S7 p. S1430-S1431
artikel
12 46MO Promoting functional persistence in solid tumor CAR T-cell therapy: Mesothelin-targeted CAR (M28z1XXPD1DNR) with T-cell intrinsic PD1 dominant negative receptor Adusumilli, P.S.

32 S7 p. S1392-S1393
artikel
13 48MO SQZ-PBMC-HPV-101: Preliminary results of a first-in-human, dose-escalation study of a cell-based vaccine in HLA A*02+ patients with recurrent, locally advanced, or metastatic HPV16+ solid tumors Park, J-C.

32 S7 p. S1393
artikel
14 Notice and Disclaimer
32 S7 p. iii
artikel
15 1O Dynamic circulating tumour DNA (ctDNA) response to neoadjuvant (NA) atezolizumab (atezo) and surgery (surg) and association with outcomes in patients (pts) with NSCLC Kris, M.G.

32 S7 p. S1373
artikel
16 3O Identification of an endogenous retroviral signature to predict PD-1 blockade response in advanced clear cell renal cell carcinoma: Integrated analysis of three clinical trials Zhou, J-G.

32 S7 p. S1375
artikel
17 2O IMpower010: Biomarkers of disease-free survival (DFS) in a phase III study of atezolizumab (atezo) vs best supportive care (BSC) after adjuvant chemotherapy in stage IB-IIIA NSCLC Zhou, C.

32 S7 p. S1374
artikel
18 4O Nivolumab (NIVO) + ipilimumab (IPI) versus chemotherapy (chemo) as first-line (1L) treatment for advanced NSCLC (aNSCLC) in CheckMate 227 part 1: Efficacy by KRAS, STK11, and KEAP1 mutation status Ramalingam, S.S.

32 S7 p. S1375-S1376
artikel
19 120O Pembrolizumab (Pembro) with or without lenvatinib (Lenva) in first-line metastatic NSCLC with PD-L1 TPS ≥1% (LEAP-007): A phase III, randomized, double-blind study Yang, J.C-H.

32 S7 p. S1429-S1430
artikel
20 121O RATIONALE 309: A randomized, global, double-blind, phase III trial of tislelizumab (TIS) vs placebo, plus gemcitabine + cisplatin (GP), as first-line treatment for recurrent/metastatic nasopharyngeal cancer (RM-NPC) Yang, Y.

32 S7 p. S1430
artikel
21 23P A comprehensive analysis of the mucosal melanoma immune microenvironment Vos, J.

32 S7 p. S1383
artikel
22 86P Adjusting ORIENT-11 trial (O-11) results to a US patient population Nagasaka, M.

32 S7 p. S1409-S1410
artikel
23 54P AKT inhibition during ex vivo tumor-infiltrating lymphocyte (TIL) expansion enhances cytokine production and function while increasing the population of less differentiated (CD39-CD69-) CD8+ T-cells Cubas, R.

32 S7 p. S1395
artikel
24 36P Alterations in tumour-promoting cytokines in cancer patients after SARS-CoV-2 infection De Winter, F.H.

32 S7 p. S1387-S1388
artikel
25 53P A multispecific non-integrating RNA CAR T platform to overcome the clinical challenge of glioblastoma heterogeneity Martínez Bedoya, D.

32 S7 p. S1395
artikel
26 45P A novel bi-functional IL15 cytokine fusion antibody selected to kill B7-H4 positive tumor cells Chang, T-P.

32 S7 p. S1391
artikel
27 183P A novel human immunocompetent platform for immunotherapy screening Marzagalli, M.

32 S7 p. S1461-S1462
artikel
28 171P An unwelcome guest: P. gingivalis intratumoral infection and immune evasion in gastric cancer Retamal, I.N.

32 S7 p. S1458
artikel
29 68P A phase Ib study of lenvatinib + pembrolizumab (LEN + PEMBRO) in patients (pts) with unresectable hepatocellular carcinoma (uHCC): Study 116 follow-up analysis Kudo, M.

32 S7 p. S1401-S1402
artikel
30 49P A phase II randomized trial with adjuvant autologous tumor lysate-pulsed dendritic cells (DC) in resected stage III-IV melanoma patients: Preliminary immunological results Ridolfi, L.

32 S7 p. S1394
artikel
31 148P A phase II study of tislelizumab plus chemotherapy in EGFR mutated advanced non-squamous NSCLC patients failed to EGFR TKI therapies: First analysis Han, B.

32 S7 p. S1443-S1444
artikel
32 18P A radiomic approach to differentiate the immunotherapy-induced pneumonitis in patients with stage IV NSCLC Romita, A.

32 S7 p. S1381
artikel
33 43P Assessment of biomarker kinetics for ADG106 (anti-CD137 agonist) as monotherapy or combined with toripalimab Zhao, H.

32 S7 p. S1389-S1390
artikel
34 161P Assessment of corticosteroid premedication for patients treated with the humanized GD2-binding monoclonal antibody naxitamab Mora, J.

32 S7 p. S1451
artikel
35 25P Association between the lung immune prognostic index (LIPI) and durvalumab consolidation outcomes in patients with locally advanced non-small cell lung cancer (NSCLC) Riudavets Melia, M.

32 S7 p. S1384
artikel
36 83P Association of lung immune prognostic index (LIPI) with progression-free survival (PFS) in soft-tissue sarcoma (STS) patients treated with immunotherapy (IO) in early phase trials Nassif, E.

32 S7 p. S1407-S1408
artikel
37 184P Association of tumor-associated neutrophils (TAN) with immunotherapy outcomes in patients in advanced non-small cell lung cancer Gorría Puga, T.

32 S7 p. S1462
artikel
38 44P Biomarker analysis from a phase Ib, multicenter, open-label clinical trial of talimogene laherparepvec (T-VEC) injected (inj) into metastatic and primary liver tumors Hecht, J.R.

32 S7 p. S1390-S1391
artikel
39 12P Blood-based biomarker analysis for predicting efficacy of definitive concurrent chemoradiotherapy and durvalumab consolidation in patients with unresectable locally advanced non-small cell lung cancer Park, C-K.

32 S7 p. S1379
artikel
40 129P BYON4228 is a pan-allelic SIRPα antibody that potentiates killing of antibody-opsonized tumor cells and lacks binding to T-cells Helden, M.V.

32 S7 p. S1433-S1434
artikel
41 42P CAMOIP: A web server for comprehensive analysis on multi-omics of immunotherapy in pan-cancer Luo, P.

32 S7 p. S1389
artikel
42 98P Camrelizumab as neoadjuvant, first- or later-line treatment for non-small cell lung cancer (NSCLC): A retrospective real-world study (CTONG2004) Xu, C.

32 S7 p. S1417
artikel
43 65P Camrelizumab combined with paclitaxel and nedaplatin as neoadjuvant therapy for locally advanced esophageal squamous cell carcinoma (ESPRIT): A phase II, single-arm, exploratory research Ma, J.

32 S7 p. S1400
artikel
44 66P Camrelizumab combined with paclitaxel and nedaplatin in the first-line treatment of locally advanced/advanced esophageal squamous cell carcinoma: A phase II, single-arm, exploratory research Wang, X.

32 S7 p. S1400
artikel
45 39P Cancers with Ochrobactrum anthropi infection show enhanced responses to immune checkpoint blockade treatment Wei, J.

32 S7 p. S1388-S1389
artikel
46 32P Can circulating immune checkpoints and KIT exon 11 mutations be prognostic factors in metastatic gastrointestinal stromal tumors? Brando, C.

32 S7 p. S1386
artikel
47 78P Cardiotoxicity in cancer patients treated with immune-checkpoint inhibitors Franco, F.F.

32 S7 p. S1406
artikel
48 73P Characteristics and outcomes of emergency presentations due to immune-mediated toxicities Nahm, S.

32 S7 p. S1403-S1404
artikel
49 14P Circulating tumor DNA (ctDNA) residual and dynamics of ctDNA clonality indicated therapeutic efficacy of sintilimab plus docetaxel in previously treated advanced non-small cell lung cancer Wang, Z.

32 S7 p. S1380
artikel
50 88P Clinical outcomes in patients with metastatic (m+) melanoma treated with immune-checkpoint inhibitors (ICI) with or without radiotherapy (RT): A monocentric retrospective study Grimaudo, M.S.

32 S7 p. S1410
artikel
51 81P Clinical value of routine FDG-PET scans as a decision tool for early immunotherapy discontinuation in advanced melanoma Ellebaek, E.

32 S7 p. S1407
artikel
52 28P Combination of tertiary lymphoid structure and neutrophil-to-lymphocyte ratio predicts survival in patients with hepatocellular carcinoma Wen, S.

32 S7 p. S1385
artikel
53 175P Combined efforts of LncRNAs DILC and atezolizumab to regulate MMP-9 release in tumor microenvironment of TNBC TAMs and cells lines Samir, A.

32 S7 p. S1459
artikel
54 69P Combining sintilimab with anlotinib as second-line or later therapy in patients with extensive-disease small cell lung cancer: A prospective, single-arm, phase II trial Shuxiang, M.

32 S7 p. S1402
artikel
55 5P Comparison of PD-L1 expression before and after neoadjuvant chemoradiation or chemotherapy in stage III non-small cell lung cancer (NSCLC) König, D.

32 S7 p. S1376
artikel
56 182P Comprehensive assessment of the immunophenotype of peripheral blood lymphocytes, inflammatory factors, the immunophenotype of lymphocytes infiltrating the tumor and clinical indicators for overall survival and progression-free survival in patients with gastric cancer Khakimova, G.

32 S7 p. S1461
artikel
57 22P Comprehensive statistical analysis of predictive markers to immune checkpoint inhibitors in patients with non-small cell lung cancer Hiltbrunner, S.

32 S7 p. S1382
artikel
58 151P CO-STAR: Surgical conversion feasibility trial of sintilimab (PD-1 inhibitor) combined with doublet chemotherapy (Nab-PTX & S-1) and apatinib (anti-angiogenic TKI) for the first-line treatment of stage IV gastric cancer (GC) Xue, Q.

32 S7 p. S1445-S1446
artikel
59 60P CXCR2 antagonist revoked TGF-β elevation in chemo-resistant triple negative breast cancer cells Ghallab, A.

32 S7 p. S1397
artikel
60 80P Defining the correlation between immune-checkpoint inhibitors-related adverse events and survival outcomes: A systematic review and meta-analysis Abdihamid, O.

32 S7 p. S1406-S1407
artikel
61 186P Determination of the number of suppressor cells of myeloid origin in blood and tumor microcirculation in patients with locally advanced and metastatic lung cancer Vukovic, J.

32 S7 p. S1463
artikel
62 30P Differential expression of miR-873, miR-181a and miR-17-5p and their correlation with immune checkpoints PD-L1 and CD155 among hepatocellular carcinoma patients Eltahtawy, O.

32 S7 p. S1385-S1386
artikel
63 7P Distinct immune gene programs associated with host tumor immunity, neoadjuvant chemotherapy and chemoimmunotherapy in resectable NSCLC Rocha, P.

32 S7 p. S1377
artikel
64 57P 3D-printable plastics compatible with CAR T-cell production Bire, S.

32 S7 p. S1396
artikel
65 134P Drugless nanoparticles tune-up immune components at triple negative breast cancer tumor microenvironment milieu Ramzy, A.

32 S7 p. S1435
artikel
66 158P Durvalumab (D) ± tremelimumab (T) + chemotherapy (CT) in first-line metastatic NSCLC (mNSCLC): Pharmacokinetics (PK) and anti-drug antibody (ADA) data from the phase III POSEIDON trial Reinmuth, N.

32 S7 p. S1449
artikel
67 34P Dynamic changes in plasma PD-L1 in patients with gliomas: Prognostic value and association with IDH status Cabezas-Camarero, S.

32 S7 p. S1387
artikel
68 17P Dynamic changes of CT-radiomic and systemic immune-inflammatory features predict the response to immune checkpoint inhibitors in advanced NSCLC patients Mazzaschi, G.

32 S7 p. S1380-S1381
artikel
69 124P Effective silencing of PD-1 gene in human peripheral blood T-lymphocytes by self-deliverable siRNA Bogdanov, A.

32 S7 p. S1432
artikel
70 185P Effect of 17β-estradiol and prolactin in the cytotoxicity of NK cells on cervical cancer cells Pereira-Suárez, A.L.

32 S7 p. S1462-S1463
artikel
71 104P Exploring the real-world impact of COVID-19 on first line (1L) treatment and management of EGFR-wild type (EGFR-WT) and ALK-wild type (ALK-WT) metastatic non-small cell lung cancer (mNSCLC) across Europe Bailey, H.

32 S7 p. S1420
artikel
72 82P Exploring treatment patterns and outcomes of patients with advanced lung cancer (aLC) using artificial intelligence (AI)-extracted data Cheung, W.Y.

32 S7 p. S1407
artikel
73 128P Ex-vivo co-blockade of CD-155/TIGIT and PD-1/PD-L1 using CCAT-1, H19 and MALAT-1 LncRNAs in hepatocellular carcinoma Youness, R.A.

32 S7 p. S1433
artikel
74 10P Family history of cancer correlates with improved outcome from immunotherapy in NSCLC independent of somatic DNA damage response gene status Cortellini, A.

32 S7 p. S1378
artikel
75 191P Fecal microbiome in soft-tissue sarcoma (STS) patients treated with neoadjuvant immune checkpoint blockade (ICB) Traweek, R.

32 S7 p. S1464
artikel
76 139P First-in-human (FIH), pharmacokinetic (PK) and pharmacodynamic (PD) study of IOA-244, a phosphoinositide 3-kinase delta (PI3Kδ) inhibitor, in patients with advanced metastatic mesothelioma, uveal and cutaneous melanoma Di Giacomo, A.M.

32 S7 p. S1438
artikel
77 135P First-in-human phase I trial of SRF617, a potent inhibitor of CD39 activity, as monotherapy or in combination, in patients (pts) with advanced solid tumors Patnaik, A.

32 S7 p. S1435-S1436
artikel
78 26P Genome-wide copy number variation of circulating cell-free DNA as a biomarker in head and neck cancer patients treated with immunotherapy Zhu, Y.

32 S7 p. S1384
artikel
79 31P Genomic landscape and actionable targets as identified by whole genome sequencing and RNA sequencing in patients with advanced renal cell carcinoma Joode, K.D.

32 S7 p. S1386
artikel
80 178P Glioblastoma multiforme cells down-regulate TNFα-mediated antitumor killer activity of dendritic cells Tyrinova, T.

32 S7 p. S1460
artikel
81 113P Health outcomes and budget impact projection of the anti-PD-(L)1 class in cancer care in Portugal Costa, L.

32 S7 p. S1424-S1425
artikel
82 163P Health-related quality of life (HRQoL) with pembrolizumab (pembro) vs chemotherapy (chemo) in platinum-pretreated recurrent or metastatic (R/M) nasopharyngeal cancer (NPC): Phase III KEYNOTE-122 study Chan, A.T.C.

32 S7 p. S1452
artikel
83 187P Hematopoietic stem cell mobilization leads to the expansion of circulating myeloid-derived suppressor cells in multiple myeloma patients Aristova, T.

32 S7 p. S1463
artikel
84 13P High neutrophils-to-lymphocyte ratio (NLR) predicts poor survival of high-PD-L1-expressing metastatic non-small cell lung carcinoma patients undergoing first-line immunotherapy with pembrolizumab Romano, F.J.

32 S7 p. S1379
artikel
85 9P HLA-I homozygosity as a predictive biomarker for developing immune related adverse events (irAE) among non-small cell lung cancer (NSCLC) patients treated with single agent immunotherapy Abed, A.

32 S7 p. S1378
artikel
86 20P Identifying novel biomarkers with deep proteomics profiling and survival analysis in NSCLC patients treated with anti-PD-1-blockade Nguyen, E.

32 S7 p. S1382
artikel
87 130P IL-2-armed oncolytic vaccinia virus exerts potent antitumor effects in human pancreatic cancer Wang, R.

32 S7 p. S1434
artikel
88 79P Immune-related adverse events are correlated with significantly improved outcome in a phase I trial population exposed to combination immunotherapy Mazzarella, L.

32 S7 p. S1406
artikel
89 112P Immunogenicity of the mRNA-1273 SARS-CoV-2 vaccine in cancer patients receiving immunotherapy agents Muñoz, F. Longo

32 S7 p. S1424
artikel
90 152P Immunotherapy-based strategies displayed a promising efficacy in non-small cell lung cancer (NSCLC) patients with non-EGFR oncogenic genetic alterations Zhang, Y.

32 S7 p. S1446
artikel
91 75P Impact of axitinib therapy management on adverse event (AE) resolution/improvement (Res/Imp) among advanced renal cell carcinoma (aRCC) patients (Pts) receiving first-line (1L) axitinib + checkpoint inhibitor (CPI) therapy Huynh, L.

32 S7 p. S1404-S1405
artikel
92 174P Impact of cabozantinib on dendritic and natural killer cell immune responses in a murine syngeneic tumor model Divoux, J.

32 S7 p. S1459
artikel
93 61P IMpower110: Exploratory analyses of the impact of first-line (1L) atezolizumab on the efficacy of next-line of therapy in PD-L1–selected NSCLC Patel, S.P.

32 S7 p. S1398-S1399
artikel
94 102P IMreal Cohort 2: First interim analysis of patient (pt) characteristics and safety data in pts with locally advanced or metastatic NSCLC (aNSCLC) receiving atezolizumab (atezo) under real-world conditions Girard, N.

32 S7 p. S1418-S1419
artikel
95 147P Inductive anti-PD-1 and albumin paclitaxel/cisplatin on pathological response in patients with locally advanced oral squamous cell carcinoma: A single arm trial Zhong, L-P.

32 S7 p. S1443
artikel
96 72P Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity Diab, A.

32 S7 p. S1403
artikel
97 40P Interplay between mutational profile and TMB on overall survival: A post hoc analysis of 1,662 metastatic patients treated with immune checkpoint inhibitors Xavier, C.B.

32 S7 p. S1389
artikel
98 149P KEYNOTE-629: Efficacy of pembrolizumab (Pembro) per immune-related RECIST (irRECIST) in locally advanced (LA) and recurrent or metastatic (R/M) cutaneous squamous cell carcinoma (cSCC) Munoz Couselo, E.

32 S7 p. S1444-S1445
artikel
99 127P Lactobacillus plantarum IMB19 exerts anti-tumor immunity by enhancing effector functions of tumor associated type 1 macrophage and CD8+ T-cells Im, S-H.

32 S7 p. S1433
artikel
100 87P Landscape of immune-checkpoint inhibitors for metastatic colorectal cancer: A meta-analysis Shek, D.

32 S7 p. S1410
artikel
101 95P Long-term outcomes in patients with BRAF-mutant advanced melanoma: A real-world study Amin, A.

32 S7 p. S1415-S1416
artikel
102 125P LSD1 inhibition restores MHC class I expression and augments the anti-tumor response of immune checkpoint blockade in small cell lung cancer Sen, T.

32 S7 p. S1432
artikel
103 76P Need for awareness about immune-related adverse events (iRAEs) among community physicians in India Koyyala, V.P.B.

32 S7 p. S1405
artikel
104 145P Neoadjuvant chemotherapy combined with camrelizumab for locally advanced head and neck squamous cell carcinoma: A phase II trial Yang, K.

32 S7 p. S1442-S1443
artikel
105 110P Neoadjuvant PD-1 blockade combined with chemotherapy for patients with resectable locally advanced esophageal squamous cell carcinoma (ESCC): A real world data analysis Lv, H.

32 S7 p. S1423
artikel
106 64P Neoadjuvant toripalimab plus chemotherapy in patients with potentially resectable non-small cell lung cancer: A prospective, single-arm, phase II trial (Renaissance Study) Yan, S.

32 S7 p. S1400
artikel
107 55P Neoantigen-reactive CD8 T-cells experience broadened and activated recognition profile following PD-L1 blockade and 1000-fold neoantigen-specific expansion using ImmPACT scaffolds Holm, J. Sejerø

32 S7 p. S1395
artikel
108 101P Nivolumab outcomes in interstitial lung disease patients with advanced non-small cell lung cancer in French real-world setting Assie, J-B.

32 S7 p. S1418
artikel
109 143P Novel anti-PD-L1 antibody TQB2450 (T) in combination with anlotinib (A) in patients with advanced soft tissue sarcoma (STS), the results from the expanded sample size and updated data Liu, J.

32 S7 p. S1442
artikel
110 126P Novel B7-H3 targeting dual nanobody NK cell engagers display robust activity against a broad spectrum of solid and hematologic malignancies Zorko, N.

32 S7 p. S1433
artikel
111 133P Novel fully human agonist antibodies against the T-cell costimulatory receptor CD27 shape adaptive anti-tumor immunity Guillaudeux, T.

32 S7 p. S1435
artikel
112 59P Oncolytic adenovirus-based therapeutics to target or reprogram glioma-associated macrophages de Sostoa, J.

32 S7 p. S1397
artikel
113 56P Optimization of manufacturing conditions CAR T-cells with 4-1BB costimulatory domain Angelats, L.

32 S7 p. S1396
artikel
114 70P Outcomes in patients treated with taxane regimen after immune checkpoint inhibitors failure in advanced or metastatic non-small cell lung cancer Guillemois, S.

32 S7 p. S1402-S1403
artikel
115 179P Paracrine crosstalk between LncRNA DILC and TNF-α release in tumor microenvironment of triple negative breast cancer El Tayebi, H.M.

32 S7 p. S1460
artikel
116 94P Patient-reported outcomes (PROs) following sintilimab (sint) plus pemetrexed (pem) and platinum (plt) based chemotherapy as first-line therapy for locally advanced or metastatic nonsquamous NSCLC: A randomized, double-blind, phase III study (Orient-11) Fang, J.

32 S7 p. S1415
artikel
117 93P Patient-reported outcomes (PROs) with cemiplimab or placebo plus platinum-doublet chemotherapy (chemo) for first-line (1L) treatment of advanced non-small cell lung cancer (aNSCLC): EMPOWER-Lung 3 trial Makharadze, T.

32 S7 p. S1414
artikel
118 35P PD-1+ and TIM-3+ T-cells differ in the expression of common γ-chain cytokine receptors after AHSCT in multiple myeloma patients Batorov, E.

32 S7 p. S1387
artikel
119 62P PD-1 inhibitor plus chemotherapy versus bevacizumab plus chemotherapy in patients with advanced non-squamous non-small cell lung cancer: A pooled analysis of three randomized trials Chen, Y.

32 S7 p. S1399
artikel
120 92P PD-L1 inhibitors as monotherapy for the first-line treatment of non-small cell lung cancer in PD-L1 positive patients: A safety data network meta-analysis García Campelo, M.R.

32 S7 p. S1413-S1414
artikel
121 37P PD-L1 on the endothelium of micrangium inside tumor: A novel predictor for the efficacy of anti-angiogenesis (anlotinib) plus anti-PD-L1 (TQ-B2450)? Ma, L.

32 S7 p. S1388
artikel
122 6P Pembrolizumab plus chemotherapy vs chemotherapy in Asian patients with PD-L1 negative advanced NSCLC: Pooled analysis of KN021G, KN189 and KN407 Cheng, Y.

32 S7 p. S1376-S1377
artikel
123 160P Pembrolizumab re-challenge in patients with relapsed non-small cell lung cancer (NSCLC): A preliminary report of the REPLAY phase II trial - cohort I Ponce Aix, S.

32 S7 p. S1450
artikel
124 159P Pembrolizumab, SBRT, and immunomodulation for recurrent and/or refractory cervical or endometrial carcinoma De Jaeghere, E.A.

32 S7 p. S1449-S1450
artikel
125 141P Phase Ib study of the TLR7 agonist TQ-A3334 monotherapy or combined with anlotinib or PD-L1 inhibitor in treatment of advanced metastatic non-small cell lung cancer Song, Y.

32 S7 p. S1440
artikel
126 91P Phase I dose escalation of IMC-C103C, a CD3×MAGE-A4 T-cell receptor (TCR) bispecific protein Davar, D.

32 S7 p. S1411-S1413
artikel
127 136P Phase I dose escalation study of MCLA-145, a bispecific antibody targeting CD137 and PD-L1 in solid tumors Prenen, H.

32 S7 p. S1436
artikel
128 137P Phase I dose-finding study of a novel anti-CTLA-4 antibody ADG116 as monotherapy in patients with advanced solid tumors Richardson, G.

32 S7 p. S1436-S1437
artikel
129 172P Phenotypic and functional heterogeneity of tissue resident memory T-cells in colorectal cancer liver metastasis Abdeljaoued, S.

32 S7 p. S1458
artikel
130 180P Photodynamic priming of pancreatic cancer: Enabling immunotherapy De Silva, P.

32 S7 p. S1460-S1461
artikel
131 108P PICTuRE: Real-world treatment pathways in stage III non-small cell lung cancer in Portugal Teixeira, M.E.

32 S7 p. S1421
artikel
132 27P Plasma-derived exosomes as biomarkers for therapy monitoring in head and neck cancer patients treated with surgery and (chemo)radiotherapy Hofmann, L.

32 S7 p. S1385
artikel
133 181P Poor response to PD-1 inhibitors in metastatic non-small cell lung cancer (mNSCLC) patients with liver metastases may be mediated by myeloid populations Makarem, M.

32 S7 p. S1461
artikel
134 162P Population pharmacokinetic modeling of tremelimumab in patients (pts) with advanced solid tumors Even, C.

32 S7 p. S1451-S1452
artikel
135 84P Predicting longer-term progression-free survival (PFS) with durvalumab after chemoradiotherapy (CRT) in unresectable stage III NSCLC using a mixture cure model (MCM) Faivre-Finn, C.

32 S7 p. S1408-S1409
artikel
136 41P Predicting response to checkpoint inhibitors using complex molecular characteristics and immunoprofiling in solid tumours Borilova, S.

32 S7 p. S1389
artikel
137 74P Predicting the risk of immunotherapy-induced versus other-cause pneumonitis in stage IV non-small cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors Tohidinezhad, F.

32 S7 p. S1404
artikel
138 21P Predictive immunological markers of anti-PD-1/PD-L1 therapy efficacy in non-small cell lung cancer Musaelyan, A.A.

32 S7 p. S1382
artikel
139 164P Preliminary results from a phase I/II study of BDC-1001, a novel HER2 targeting TLR7/8 immune-stimulating antibody conjugate (ISAC), in patients (pts) with advanced HER2-expressing solid tumors Sharma, M.R.

32 S7 p. S1453-S1454
artikel
140 140P Preliminary results from PROPEL: A phase I/II study of bempegaldesleukin (BEMPEG: NKTR-214) plus pembrolizumab (PEMBRO) with or without chemotherapy in patients with metastatic NSCLC Felip, E.

32 S7 p. S1438-S1440
artikel
141 138P Preliminary safety and efficacy results from phase Ib study of the anti-CTLA-4 monoclonal antibody (mAb) CS1002 in combination with anti-PD-1 mAb CS1003 in patients with advanced solid tumors Bishnoi, S.

32 S7 p. S1437-S1438
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142 8P Pre-treatment blood gene expression changes associated with durable clinical benefit in metastatic non-small cell lung cancer with high PD-L1 expression receiving first-line pembrolizumab Elshiaty, M.

32 S7 p. S1377-S1378
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143 189P Prognostic significance of lymphocyte activation gene-3 (LAG3 gene) in uveal melanoma patients Singh, L.

32 S7 p. S1463-S1464
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144 173P Pseudotime dynamics in pancreatic ductal adenocarcinoma reveal different mechanisms of hindrance in immunity through bifurcation of regulatory and cytotoxic T-cell differentiation Jainarayanan, A.K.

32 S7 p. S1458-S1459
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145 146P Randomized phase II trial of neoadjuvant chemotherapy with modified FOLFIRINOX versus modified FOLFIRINOX and PD-1 antibody for borderline resectable and locally advanced pancreatic cancer (the CISPD-4 study) Chen, Y.

32 S7 p. S1443
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146 106P Real-world outcomes in extensive-stage small cell lung cancer with PD-L1 inhibitors in China Meng, X.

32 S7 p. S1420-S1421
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147 111P Real-world treatment modification of first-line axitinib + pembrolizumab in patients with metastatic renal cell carcinoma (mRCC) Zakharia, Y.

32 S7 p. S1423-S1424
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148 103P Real-world treatment patterns before and after receiving PD-L1 test results in patients (pts) with advanced non-small cell lung cancer (aNSCLC) Antonia, S.J.

32 S7 p. S1419-S1420
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149 33P Relation of T-cell infiltration and PD-L1 expression with IDH and MGMT status in gliomas: Prognostic value and role for immunotherapy development Cabezas-Camarero, S.

32 S7 p. S1387
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150 154P Results of an open-label, phase Ia/Ib study of olaratumab plus pembrolizumab in patients with unresectable, locally advanced or metastatic soft tissue sarcoma Schöffski, P.

32 S7 p. S1447
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151 71P Safety and efficacy of salvage radiotherapy after progression to checkpoint inhibitors in recurrent and/or metastatic head and neck cancer Cabezas-Camarero, S.

32 S7 p. S1403
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152 156P Safety/tolerability and antitumor activity of sitravatinib plus tislelizumab in patients with PD-(L)1-refractory/resistant unresectable or metastatic melanoma from a phase Ib study Cui, C.

32 S7 p. S1448
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153 153P Safety/tolerability and antitumor activity of sitravatinib plus tislelizumab (TIS) in patients with advanced platinum-resistant ovarian cancer (PROC) Goh, J.C.

32 S7 p. S1446-S1447
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154 11P Senescent immune phenotype (SIP) status that predicts resistance to immune checkpoint blockers (ICB) among CMV+ advanced non-small cell lung cancer (aNSCLC) patients is not associated with chronic type I IFN signature Naigeon, M.

32 S7 p. S1379
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155 15P Serum immune checkpoint biomarkers as predictors of response to anti-PD-1/PD-L1 treatment in non-small cell lung cancer (NSCLC) patients Raza, A.

32 S7 p. S1380
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156 90P Sex difference in side effects of immunotherapy in a population of patients with non-small cell lung cancer Valota, M.

32 S7 p. S1411
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157 63P Shifting treatment landscape and overall survival (OS) by PD-L1 expression level among patients (pts) with advanced non-small cell lung cancer (aNSCLC) Dietz, H.

32 S7 p. S1399-S1400
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158 67P Sintilimab, doxorubicin and ifosfamide (AI) as first-line treatment in patients with advanced soft tissue sarcoma: A single-arm phase II trial Luo, Z.

32 S7 p. S1401
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159 100P SPOTLIGHT real-world study: Patient characteristics and treatment patterns in patients with unresectable stage III NSCLC receiving durvalumab after chemoradiotherapy (CRT) Mooradian, M.J.

32 S7 p. S1417-S1418
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160 16P Stromal compartment specific gene signatures dissect immunotherapy response groups in non-small cell lung cancer Kulasinghe, A.

32 S7 p. S1380
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161 150P Subgroup analysis of ORIENT12: Efficacy of sintilimab in combination with gemcitabine and platinum-based chemotherapy in patients with advanced or metastatic squamous non-small cell lung cancer Zhou, C.

32 S7 p. S1445
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162 155P Surufatinib plus toripalimab for second-line treatment of advanced gastric or gastroesophageal junction (G/GEJ) adenocarcinoma, esophageal squamous cell carcinoma (ESCC) and neuroendocrine carcinoma (NEC): A multicenter, single-arm phase II study Lu, M.

32 S7 p. S1448
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163 157P Surufatinib plus toripalimab in patients with advanced small cell lung cancer (SCLC) after failure of first-line systemic chemotherapy Cheng, Y.

32 S7 p. S1448-S1449
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164 89P Survival and immunotoxicity profiles in younger versus elderly patients with metastatic renal cell cancer undergoing immunotherapy Zhang, J.

32 S7 p. S1410-S1411
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165 38P The association between albumin-globulin ratio (AGR) and survival in patients treated with immune checkpoint inhibitors Guven, D.C.

32 S7 p. S1388
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166 85P The association between diabetes and survival in patients treated with immunotherapy Guven, D.C.

32 S7 p. S1409
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167 77P The Belgian Multidisciplinary Immunotoxicity Board (BITOX): A nationwide initiative of the Belgian Society of Medical Oncology (BSMO) Verhaert, M.

32 S7 p. S1405
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168 107P The evolving diagnostic and treatment landscape in metastatic non-small cell lung cancer (mNSCLC) across Europe: A real world evidence survey Bailey, H.

32 S7 p. S1421
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169 52P The inducible Medigene T-cell receptor (iM-TCR) controls cytotoxicity of tumor-specific TCR-modified T-cells with improved avidity through control of TCR surface expression Acs, A.

32 S7 p. S1394
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170 29P The multi-switching activity of circulatory neutrophils in patients with early breast cancer Ramessur, A.

32 S7 p. S1385
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171 19P Therapeutic targets in non-small cell lung cancer: Preclinical and human studies of carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) expression and its associated molecular landscape Adam, J.

32 S7 p. S1381
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172 188P TIM-3 expression and markers of immune escape on leukemia cells Kuzelova, K.

32 S7 p. S1463
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173 144P Tislelizumab combined with chemotherapy as neoadjuvant therapy for surgically resectable esophageal cancer (TD-NICE): A single arm, phase II study Yan, X.

32 S7 p. S1442
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174 177P TP53 and PRBM1 mutations predict “hot” tumor microenvironment in intrahepatic cholangiocarcinoima Lozzi Da Costa, I.

32 S7 p. S1460
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175 190P Transcriptomic molecular subtypes of esophageal squamous cell carcinoma predicted the prognosis and efficacy of neo-adjuvant immunotherapy Liu, J.

32 S7 p. S1464
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176 131P Translating a novel autotaxin inhibitor from preclinical proof of concept in pancreatic cancer to a biomarker response in human subjects Milleri, S.

32 S7 p. S1434
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177 51P Translational analyses of the DeCidE phase II clinical study in advanced ovarian cancer patients reveal a substantial role for B-cells in the clinical benefit derived from maveropepimut-S (MVP-S) treatment Dorigo, O.

32 S7 p. S1394
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178 109P Treatment patterns in patients with advanced non-small cell lung cancer (aNSCLC) after discontinuing an immune checkpoint inhibitor (ICI) therapy in second-line or later in Germany and France Griesinger, F.

32 S7 p. S1422-S1423
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179 97P Trends and disparities in real-world (RW) biomarker testing (BT) and overall survival (OS) among US patients (pts) with advanced non-small cell lung cancer (aNSCLC), 2015–2020 Antonia, S.J.

32 S7 p. S1416-S1417
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180 132P Tumor-responsive nanoparticles exhibit selective immunomodulatory effects: A Trojan horse strategy Sebak, A.

32 S7 p. S1434
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181 176P Type of TP53 alteration may correlate with the extent of lymphocytic infiltration in high-grade serous ovarian carcinomas Sokolenko, A.

32 S7 p. S1459
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182 142P Updated results from a phase I, open-label, multicenter, first-in-human study of AMG 404, a checkpoint inhibitor, in patients with advanced solid tumors Price, T.J.

32 S7 p. S1440-S1442
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183 24P Using real-world evidence data and machine learning to identify molecular biomarkers for patient response to immune checkpoint inhibitors in metastatic melanoma Siozopoulou, V.

32 S7 p. S1383
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184 96P US real-world immunotherapy-based treatment patterns and clinical outcomes of advanced NSCLC (aNSCLC) patients in the first-line setting Bittoni, M.A.

32 S7 p. S1416
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185 105P US real-world treatment patterns and outcomes of metastatic nonsquamous non-small cell lung cancer (mNSQ NSCLC) patients (pts) after progression on standard of care (SOC) Bittoni, M.A.

32 S7 p. S1420
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186 58P Validation of the Achilles VELOS process 2 manufacturing platform for the treatment of solid cancer: GMP scale runs generate a significant dose boost of highly potent clonal neoantigen reactive T-cells Samuel, E.R.

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187 Table of Contents
32 S7 p. vii
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188 167TiP AdvanTIG-301: Anti-TIGIT monoclonal antibody (mAb) ociperlimab (OCI) + tislelizumab (TIS) + concurrent chemoradiotherapy (cCRT) followed by OCI + TIS or TIS + cCRT followed by TIS vs cCRT followed by durvalumab (DUR) in previously untreated, locally advanced, unresectable NSCLC Xing, L.

32 S7 p. S1455
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189 165TiP A first-in-human phase I study of FS222, a CD137/PD-L1 tetravalent bispecific antibody, in patients with advanced malignancies Garralda, E.

32 S7 p. S1454
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190 118TiP A multicenter, randomized, double-blind, placebo-controlled phase III trial of camrelizumab plus chemotherapy with or without radiation therapy (RT) as first-line treatment for patients with brain metastatic non-small cell lung cancer (BM-NSCLC; CTONG2003): Trial in progress Yang, J.

32 S7 p. S1426-S1427
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191 117TiP A phase II study of toripalimab combined with paclitaxel/carboplatin for the first-line treatment of advanced thymic carcinoma Hu, X.

32 S7 p. S1426
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192 170TiP A phase I study to characterize the safety and tolerability of MP0317, a tumor targeting FAP dependent CD40 agonist DARPin®, in patients with relapsed/refractory solid tumors Jeger, S.

32 S7 p. S1456-S1457
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193 119TiP Dual-immunotherapy and short-course medium-dose radiotherapy, followed by surgery for tumor microenvironment modification in early stage NSCLC: The DIRECT-trial Dickhoff, C.

32 S7 p. S1427
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194 168TiP KEYNOTE-A86: Phase III, randomized, open-label study of first-line subcutaneous (SC) vs intravenous (IV) pembrolizumab with platinum doublet chemotherapy in metastatic squamous or nonsquamous non-small cell lung cancer (NSCLC) Halmos, B.

32 S7 p. S1456
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195 116TiP KEYNOTE-B98: Phase Ib/II study of pembrolizumab plus investigational agents as second-line treatment for anti–PD-1/PD-L1-refractory extensive-stage small cell lung cancer (ES-SCLC) Lai, W.C.V.

32 S7 p. S1425-S1426
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196 114TiP KEYNOTE-B99: Phase II study of pembrolizumab plus investigational agents combined with chemotherapy as first-line therapy for extensive-stage small cell lung cancer (ES-SCLC) Peled, N.

32 S7 p. S1425
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197 166TiP Pembrolizumab combined with neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy followed surgery for locally advanced esophageal squamous cell carcinoma: Protocol for a multi-center, prospective, randomized-controlled, phase III clinical study (Keystone-002) Jiang, H.

32 S7 p. S1454-S1455
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198 115TiP Stereotactic body radiotherapy (SBRT) plus anlotinib with or without toripalimab in driver mutation-negative non-small cell lung cancer (NSCLC) patients with untreated brain oligometastatic metastases: A prospective, single-center, phase Ib study Han, G.

32 S7 p. S1425
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199 169TiP Tocilizumab, ipilimumab, and nivolumab for the treatment of advanced melanoma, non-small cell lung cancer, or urothelial carcinoma Diab, A.

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200 Title Page
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                             200 gevonden resultaten
 
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